EXPRESSION AND FUNCTION OF THE HOMEOSTATIC MOLECULE DEL-1 IN ENDOTHELIAL CELLS AND THE PERIODONTAL TISSUE

Developmental endothelial locus-1 (Del-1) is an endothelial cell-secreted protein that limits the recruitment of neutrophils by antagonizing the interaction between the LFA-1 integrin on neutrophils and the intercellular adhesion molecule (ICAM)-1 on endothelial cells.Mice with genetic or age-associated Del-1 deficiency exhibit increased neutrophil

The occurrence of a new coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), quickly became a global threat after it had spread across the continents in just a few months.Over the next three years, it caused infections in over 646.6 million people and resulted in over 6.6 million Dab Inserts deaths.As a novel disease, Coronavi